1,414 thoughts on “General Discussion – 2

  1. I recommend reading the entire article below at the link

    https://www.infectioncontroltoday.com/view/weekly-rounds-with-infection-control-today-covid-19-s-much-worse-than-flu-long-covid-s-effect-on-kids-universal-masking

    Viewpoint: Here’s Why COVID-19 Is Much Worse Than Flu
    October 1, 2021
    Kevin Kavanagh, MD

    COVID-19 has a number of presentations and pulmonary is just one. More than anything else, the receptor used for attachment determines the behavior of any virus, along with what organs and even species it can infect.

    Human rhinoviruses, the most common cause of a cold, uses the ICAM-1 (intercellular adhesion molecule-1) receptor to enter cells. This receptor allows the virus to replicate in sinus tissues but not to a variety of other tissues. The influenza virus attaches to cells via sialic acid receptors, which are sugar-protein and sugar-fat complexes. There are a number of modifications of this receptor across species, which require differing viral mutations to enable cellular attachment and entry. The influenza virus primarily targets a patient’s lungs, but then the patient’s immune response can also produce a myriad of system symptoms from loss of appetite and myalgias. HIV uses the CD4 receptor residing on Lymphocytes. HIV is initially asymptomatic, and the initial stages of disease can easily be classified as “mild”, a disease which, if left untreated, almost uniformly turns aggressive and fatal over the course of 8 to 10 years.

    In the case of SARS-CoV-2, the virus which causes COVID-19, the ACE2 receptor is used for viral entry into the cells. The ACE2 receptor is entirely different to that used by the rhinovirus and seasonal flu. It is composed of amino acids along with a zinc ligand. This receptor is present throughout the body, not just the lungs.

    Clinically, SARS-CoV-2 combines some of the properties of the seasonal flu plus HIV. Similar to the seasonal flu, SARS-CoV-2 can primarily attack the lungs. But ACE2 receptors are everywhere. Similar to HIV, the virus can also enter a stealth mode, silently spreading throughout the host’s body and attacking almost every organ, especially those with a high ACE2 receptor concentration. And similar to HIV, SARS-CoV-2 also frequently causes asymptomatic spread. In full stealth mode, SARS-CoV-2 can asymptomatically attack the vasculature and heart. Myocarditis can occur and the patient is totally unaware of the damage, until an arrhythmia or symptomatic myocarditis develops. In young asymptomatic patients, this is not an uncommon sequela.

    SARS-CoV-2 targeting the cardiovascular system of the body should be a given. It has been known for a long time that ACE receptors are involved in cardiovascular regulation. ACE inhibitors and ACE II blockers have long been used to treat high blood pressure. This is the same pathway the virus infects.

    Thus, there are multiple presentations of SARS-CoV-2 including pulmonary, cardiac, gastrointestinal (GI), and central nervous system (CNS).

  2. https://www.dailymail.co.uk/news/article-10052689/Government-condemned-refusing-release-details-key-email-conversations-Covid-origins.html

    What are they hiding? At the start of Covid many scientists believed it likely leaked from Wuhan lab – until a conference call with Patrick Vallance changed their minds. We asked for his emails about the call. This is what we got . . .

    This newspaper used Freedom of Information rules to obtain a cache of 32 emails about a secretive teleconference between British and American health officials held early in the pandemic.

    But officials blacked out almost every word before releasing the crucial documents.

    Before this discussion, several of the world’s most influential experts believed the new virus most likely came from a laboratory – but days later, the scientists began dismissing such scenarios as ‘implausible’ and branding them conspiracy theories.

    The critical call is at the centre of concerns that the scientific establishment tried to stifle debate on the pandemic’s origins, as damning new evidence emerges of US ties to high-risk research on bat viruses in Wuhan, where the first cases emerged in late 2019.

  3. https://www.news18.com/news/india/punjab-sees-power-cut-for-2-3-hrs-due-to-coal-shortage-4303610.html

    After Rajasthan, Punjab Says it Will Cut Power for 2-3 Hrs Due to Nationwide Coal Shortage

    Severe coal shortage in the country has started impacting power generation in many states with Punjab effecting a power cut of three to four hours across the state on Saturday. A day ago, Rajasthan had also said that it will schedule one-hour power cuts.

    Officials of state owned Punjab State Power Corporation Lmited (PSPCL) said two units each at Talwandi Sabo power plant, Ropar plant and one unit at the Lehra Mohabbat plant have been shut.

    While the units at the Lehra Mohabbat plant and Talwandi Sabo plant have been forced to shut because of coal shortage, technical glitches have forced the shut down of two units at Ropar. This has led to a power shortage of 1,000 MW

    …Over half of India’s 135 coal-fired power plants, which in total supply around 70% of the country’s electricity, have fuel stocks of less than three days, data from the federal grid operator showed.

  4. https://news.sky.com/story/lebanon-total-power-outage-as-electricity-grid-shuts-down-after-running-out-of-fuel-reports-12429825

    Lebanon: Total power outage as electricity grid shuts down after running out of fuel – reports

    Lebanon’s electricity grid has shut down entirely after the country’s two main power stations ran out of fuel, according to reports.

    The al Zahrani and the Deir Ammar power stations stopped working after supplies of diesel were apparently exhausted, and energy production dropped to below 200 megawatts.

    The outage will continue for a few days, at least, Reuters news agency has said, quoting an official source.

  5. Keeping an eye on this sub variant of Delta which appears to be growing fast in the UK – AY.4.2

    https://twitter.com/HarrySpoelstra/status/1447477781193969674

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