1,435 thoughts on “General Discussion – 2

  1. I recommend reading the entire article below at the link

    https://www.infectioncontroltoday.com/view/weekly-rounds-with-infection-control-today-covid-19-s-much-worse-than-flu-long-covid-s-effect-on-kids-universal-masking

    Viewpoint: Here’s Why COVID-19 Is Much Worse Than Flu
    October 1, 2021
    Kevin Kavanagh, MD

    COVID-19 has a number of presentations and pulmonary is just one. More than anything else, the receptor used for attachment determines the behavior of any virus, along with what organs and even species it can infect.

    Human rhinoviruses, the most common cause of a cold, uses the ICAM-1 (intercellular adhesion molecule-1) receptor to enter cells. This receptor allows the virus to replicate in sinus tissues but not to a variety of other tissues. The influenza virus attaches to cells via sialic acid receptors, which are sugar-protein and sugar-fat complexes. There are a number of modifications of this receptor across species, which require differing viral mutations to enable cellular attachment and entry. The influenza virus primarily targets a patient’s lungs, but then the patient’s immune response can also produce a myriad of system symptoms from loss of appetite and myalgias. HIV uses the CD4 receptor residing on Lymphocytes. HIV is initially asymptomatic, and the initial stages of disease can easily be classified as “mild”, a disease which, if left untreated, almost uniformly turns aggressive and fatal over the course of 8 to 10 years.

    In the case of SARS-CoV-2, the virus which causes COVID-19, the ACE2 receptor is used for viral entry into the cells. The ACE2 receptor is entirely different to that used by the rhinovirus and seasonal flu. It is composed of amino acids along with a zinc ligand. This receptor is present throughout the body, not just the lungs.

    Clinically, SARS-CoV-2 combines some of the properties of the seasonal flu plus HIV. Similar to the seasonal flu, SARS-CoV-2 can primarily attack the lungs. But ACE2 receptors are everywhere. Similar to HIV, the virus can also enter a stealth mode, silently spreading throughout the host’s body and attacking almost every organ, especially those with a high ACE2 receptor concentration. And similar to HIV, SARS-CoV-2 also frequently causes asymptomatic spread. In full stealth mode, SARS-CoV-2 can asymptomatically attack the vasculature and heart. Myocarditis can occur and the patient is totally unaware of the damage, until an arrhythmia or symptomatic myocarditis develops. In young asymptomatic patients, this is not an uncommon sequela.

    SARS-CoV-2 targeting the cardiovascular system of the body should be a given. It has been known for a long time that ACE receptors are involved in cardiovascular regulation. ACE inhibitors and ACE II blockers have long been used to treat high blood pressure. This is the same pathway the virus infects.

    Thus, there are multiple presentations of SARS-CoV-2 including pulmonary, cardiac, gastrointestinal (GI), and central nervous system (CNS).

  2. https://www.dailymail.co.uk/news/article-10052689/Government-condemned-refusing-release-details-key-email-conversations-Covid-origins.html

    What are they hiding? At the start of Covid many scientists believed it likely leaked from Wuhan lab – until a conference call with Patrick Vallance changed their minds. We asked for his emails about the call. This is what we got . . .

    This newspaper used Freedom of Information rules to obtain a cache of 32 emails about a secretive teleconference between British and American health officials held early in the pandemic.

    But officials blacked out almost every word before releasing the crucial documents.

    Before this discussion, several of the world’s most influential experts believed the new virus most likely came from a laboratory – but days later, the scientists began dismissing such scenarios as ‘implausible’ and branding them conspiracy theories.

    The critical call is at the centre of concerns that the scientific establishment tried to stifle debate on the pandemic’s origins, as damning new evidence emerges of US ties to high-risk research on bat viruses in Wuhan, where the first cases emerged in late 2019.

  3. https://www.news18.com/news/india/punjab-sees-power-cut-for-2-3-hrs-due-to-coal-shortage-4303610.html

    After Rajasthan, Punjab Says it Will Cut Power for 2-3 Hrs Due to Nationwide Coal Shortage

    Severe coal shortage in the country has started impacting power generation in many states with Punjab effecting a power cut of three to four hours across the state on Saturday. A day ago, Rajasthan had also said that it will schedule one-hour power cuts.

    Officials of state owned Punjab State Power Corporation Lmited (PSPCL) said two units each at Talwandi Sabo power plant, Ropar plant and one unit at the Lehra Mohabbat plant have been shut.

    While the units at the Lehra Mohabbat plant and Talwandi Sabo plant have been forced to shut because of coal shortage, technical glitches have forced the shut down of two units at Ropar. This has led to a power shortage of 1,000 MW

    …Over half of India’s 135 coal-fired power plants, which in total supply around 70% of the country’s electricity, have fuel stocks of less than three days, data from the federal grid operator showed.

  4. https://news.sky.com/story/lebanon-total-power-outage-as-electricity-grid-shuts-down-after-running-out-of-fuel-reports-12429825

    Lebanon: Total power outage as electricity grid shuts down after running out of fuel – reports

    Lebanon’s electricity grid has shut down entirely after the country’s two main power stations ran out of fuel, according to reports.

    The al Zahrani and the Deir Ammar power stations stopped working after supplies of diesel were apparently exhausted, and energy production dropped to below 200 megawatts.

    The outage will continue for a few days, at least, Reuters news agency has said, quoting an official source.

  5. Keeping an eye on this sub variant of Delta which appears to be growing fast in the UK – AY.4.2

    https://twitter.com/HarrySpoelstra/status/1447477781193969674

  6. https://edition.cnn.com/2021/10/20/europe/russia-elderly-stay-home-order-record-deaths-intl/index.html

    Moscow orders unvaccinated over-60s to stay home for 4 months as Russia’s Covid-19 crisis deepens

    Moscow (CNN)Millions of Russians face strict new Covid-19 restrictions from this week after a slow vaccination drive, an overwhelmed health care system and widespread mistrust in government combined to plunge the country into its most deadly phase of the pandemic to date.
    On Tuesday Moscow’s mayor ordered all unvaccinated residents over 60, as well as unvaccinated people “suffering from chronic diseases,” to remain home for four months until late February as the city grapples with a growing crisis.
    The national government has also proposed introducing a non-working week at the start of November, and senior figures have started openly admitting that the situation is dire as Russians head towards a bleak winter.

    Russia has reported its highest numbers of daily cases and deaths multiple times in recent days, and it registered a record 1,028 official fatalities on Wednesday.

    Experts point towards a lagging vaccination program and a failure in government messaging as factors behind the surge, which is now threatening to deluge hospitals across the nation.
    “I think the country is now falling into disaster,” Vasily Vlassov, a Russian epidemiologist and former adviser to the World Health Organization (WHO), told CNN.

  7. https://www.france24.com/en/europe/20211020-putin-keeps-russian-workers-home-for-a-week-as-covid-deaths-surge

    Putin keeps Russian workers home for a week as Covid deaths surge

    Russian President Vladimir Putin on Wednesday backed the Cabinet’s proposal to declare a non-working week and keep Russian workers away from their offices as coronavirus deaths surged to another daily record.

    The government task force on Wednesday reported 1,028 coronavirus deaths over the past 24 hours, the highest number since the start of the pandemic. That brought Russia’s total death toll to 226,353 which is by far the highest in Europe.

    Putin said Wednesday he supports the Cabinet’s proposal to introduce a nonworking period starting Oct. 30 and extending through the following week, when four of seven days already are state holidays. He added in some regions where the situation is the most threatening, the non-working period could start as early as Saturday.

    In some regions, mounting infections forced authorities to suspend medical assistance to the population as health care facilities were forced to focus on treating coronavirus patients.

  8. https://www.bloomberg.com/news/articles/2021-10-19/china-s-curbs-on-fertilizer-exports-to-worsen-global-price-shock

    China’s Curbs on Fertilizer Exports to Worsen Global Price Shock

    Chinese authorities are imposing new hurdles for fertilizer exporters amid growing concerns over surging power prices and food production, a move that could worsen a global price shock and food inflation.

    Some Chinese fertilizer cargoes ready to be shipped are being held up by local authorities for additional checks or to obtain new export certificates, according to people familiar with the matter. The supplies will either end up being sold on the domestic market or face delays in being exported, said the people, who asked not to be named as they are not authorized to speak on the matter.

    The increased scrutiny comes as global fertilizers costs have soared to new records, spurred by energy crises in Europe and China as coal and natural gas are important feedstocks. The cost increase comes at a particularly worrying time, with global food prices hitting a 10-year high.

    China’s move to curb fertilizer exports will be felt around the world as it is a key supplier of urea, sulphate and phosphate, accounting for about 30% of global trade. The biggest buyers of China’s fertilizers include India, Pakistan and countries in Southeast Asia.

    There are already signs that a fertilizer shortage is emerging globally. Farmers in Brazil reported that some deliveries of fertilizer and glyphosate have been canceled. France, the largest European agriculture producer, may face difficulties sourcing fertilizer supplies, an official at FranceAgriMer warned last week.

  9. Way back at the start of this covid nightmare a few people posted links to “Swiss Propaganda Research” claiming that this was just an ordinary coronavirus and if it was allowed to run through a population it would be no worse than a usual year. And I said that was a pile of shite. Seems they agree with me that was a pile of shite now.

    https://swprs.org/on-the-origin-of-sars-coronavirus-2/

    On the Origin of SARS Coronavirus 2

    A comprehensive summary of facts about the origin of the novel coronavirus (SARS-CoV-2).

    Executive summary: The currently available evidence supports a lab-related origin of the novel coronavirus.

    The phylogenetic evidence links SARS-CoV-2 to a 2012 covid-like pneumonia incident in a Chinese mine near Mojiang. The virus samples of this incident were collected, stored and investigated by the Wuhan Institute of Virology (WIV). However, some US labs may also have had access to this data, as they were collaborating with the Wuhan lab in the field of coronavirus research. At the genetic level, the existence of a furin cleavage site involving a CGG-coded double arginine codon may indicate genetic engineering. The search for an intermediate animal host has so far remained unsuccessful, but a natural origin cannot yet be ruled out entirely.

  10. Meet the likely AY.4.2.something – seems to have already become the dominant “flavour” of AY.4.2 in Scotland and with a higher calculated transmission advantage than its parent. The transmission advantage is based on UK wide detection which is why that proportion is lower as it may have arisen in Scotland. So we seem to have the most transmissible variant of Delta, detected so far, well established and growing fast in Scotland just in time for lots of people to come to Glasgow for COP26.

    https://cov-spectrum.ethz.ch/explore/United%20Kingdom/AllSamples/AllTimes/variants?aaMutations=S%3AV1264L&pangoLineage=AY.4.2

  11. https://twitter.com/hjelle_brian/status/1453058225104822277

  12. https://www.timesofisrael.com/bennett-to-parents-there-is-no-reason-not-to-vaccinate-your-children/

    Holed up in nuke bunker for COVID drill, Bennett tells parents: Vaccinate kids


    Prime Minister Naftali Bennett in an underground bunker during a COVID-19 drill, on November 11, 2021. (Haim Zach/GPO)

    Holed up in a nuclear-safe bunker during an unprecedented COVID drill, Prime Minister Naftali Bennett on Thursday called on parents of 5- to 11-year-olds to inoculate their children, as Israel expands its vaccine drive to its youngest population yet.

    “There is no reason to leave our children unprotected,” Bennett said, speaking from the underground bunker during a simulation testing nationwide preparations for a hypothetical outbreak of a new, lethal, COVID-19 variant.

    The day-long “Omega Drill,” named for a fictitious variant of the virus, is said to be the first of its kind held anywhere in the world.

    “There is no reason that your child should get infected and infect others when his whole life is ahead of him,” the premier said. “I call on parents – vaccinate your children. Safeguard them. Give them the same layer of protection that you have.”

    The Health Ministry approved expanding the country’s vaccine drive to children on Wednesday evening, following the lead of the United States Food and Drug Administration.

  13. https://www.theguardian.com/world/2021/nov/12/partial-lockdown-in-netherlands-amid-record-covid-cases

    Netherlands imposes lockdown measures as Covid cases hit new high

    The Netherlands will become the first western European country to impose a partial lockdown since the summer, introducing strict new measures from Saturday in the face of record numbers of new Covid-19 infections.

    The restrictions, announced by the caretaker prime minister, Mark Rutte, on Friday, will last at least three weeks and include the closure of bars, restaurants and essential shops from 8pm, with non-essential retail and services such as hairdressers to close at 6pm.

    Gatherings at home would be limited to a maximum of four guests, all amateur and professional sporting events must be held behind closed doors, and home working was advised except in “absolutely unavoidable” circumstances, Rutte said.

    …“The virus is everywhere and needs to combated everywhere. I want every Dutch citizen to be asking, can I do more? Can I do better? We had hoped with the vaccines we wouldn’t have to do this, but we see the same situation all across Europe.”

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